0 0.00

Shopping Cart ( 0 )

Your Have 0 Item In Your Cart


No products in the cart.

Efficacy on Lambda Variant : SARS-CoV-2 Lambda variant Mutation Report

  • Home
  • Efficacy on Lambda Variant : SARS-CoV-2 Lambda variant Mutation Report

SARS-CoV-2 Lambda variant Mutation (lineage C.37):

The SARS-CoV-2 Lambda variant, also known as lineage C.37, is a variant of SARS-CoV-2, the virus that causes COVID-19. It was first detected in Peru in December 2020. On 14 June 2021, the World Health Organization (WHO) named it Lambda variant and designated it as a variant of interest. It has spread to at least 30 countries] around the world and may be more resistant to COVID-19 vaccines compared to other strains. It is also suggested that the Lambda variant is more infectious than the Alpha or Gamma variant.


The Lambda genome has the following amino acid mutations, all of which are in the virus’s spike protein code: G75V, T76I, Δ246-252, L452Q, F490S, D614G and T859N.

The E484Q mutation is present in the B.1.617.2 genome.


The Lambda variant has mutations in the gene encoding the SARS-CoV-2 spike protein causing the substitutions Del246_252, F490S, G75V, L452Q, T76I, T859N and D614G.


The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new coronavirus associated with severe acute respiratory syndrome. We used a molecular docking protocol to anticipate possible sites for nine ligands from the Protein Data Bank’s twelve SARS-CoV-2 Lambda variant Mutation proteins. The current analysis reveals that 7 mutated SARS-CoV-2 Lambda variant Mutation protein interacted with nine ligands and showed the best interaction with all Del246_252, F490S, G75V, L452Q, T76I, T859N and D614G with binding energy greater than -5.00 (kcal/mol). Using Docking research, all nine compounds of Vedicinal 9 had the best interactions with the mutant protein. As shown by the single asterisk (*), the binding energies range from -5.01 to -6.99 kcal/mol, indicating a promising result and excellent binding energy. The range of -7.01 to -8.99, shown by a double asterisk (**), indicates a high binding energy and is extremely effective against the SARS-CoV-2 Lambda mutation.